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The Impact of AlphaFold 3’s Open Source Release on Life Sciences, Medicine, and Pharmacology: Applications and Practical Guidance

AlphaFold 3 (AF3), developed by Google DeepMind, represents a major advancement in the field of biomolecular structure prediction. It is a state-of-the-art AI tool specifically designed to predict and analyze the three-dimensional structures of complex biomolecules and their interactions, encompassing proteins, DNA, RNA, and other biomolecules. AF3 transcends the limitations of previous versions by employing […]

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Imperfect AI Large Models Still Powerfully Propel Professional Fields

In recent years, artificial intelligence (AI) technology has advanced rapidly, especially with the increasingly widespread application of large models such as GPT-4, Claude, Gemini, WuDao 2.0, ERNIE, and PanGu-α. From natural language processing to image recognition and autonomous driving, AI large models have demonstrated immense potential across various fields. However, despite their outstanding capabilities in […]

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Application of Artificial Intelligence Models in Simulating and Prediction of Severe Cases After COVID-19 Infection

I. Generation of Simulation Data: To clearly present the analysis results, post-infection clinical symptoms of the virus are simulated using the common case-control pattern, simulating both severe and mild patients. Considering that some clinical phenotypic data (such as age) are highly correlated with post-infection symptoms, we set up 2 strongly correlated features. Additionally, we established […]